Evaluation of two DNA amplification PCR tests for the diagnosis of Clostridium difficile infection
نویسندگان
چکیده
منابع مشابه
Evaluation of the Xpert Clostridium difficile Assay for the Diagnosis of Clostridium difficile Infection
Infection with Clostridium difficile is a growing concern because of the increasing prevalence and spread of nosocomial infections. Emergence of the hypervirulent 027/NAP1/BI strain is also notable. Existing diagnostic methods have low sensitivity or are time-consuming. Therefore, establishing a rapid and accurate microbiological diagnostic assay is needed. We evaluated the Xpert C. difficile a...
متن کاملEvaluation of diagnostic tests for Clostridium difficile infection.
We evaluated toxigenic Clostridium difficile detection by a lateral flow assay for antigen and toxin, an enzyme immunoassay, and two commercial PCR methods. Compared to the cell cytotoxicity neutralization assay and toxigenic culture, both toxin detection methods lacked sensitivity. PCR following combined antigen and toxin detection provided the most useful diagnostic information.
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Clostridium difficile is the most common infectious cause of nosocomial diarrhea, affecting thousands of patients annually and exacting enormous costs on the U.S. health care system. Early diagnosis is critical to prevent transmission and reduce morbidity and mortality, yet sensitive and specific diagnostic tests with a quick turnaround time are lacking. The objective of this study was to deter...
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abstract this study evaluated and compared medical terminology and english for the students of medicine (ii) as two representatives of the textbooks available on the iranian market for teaching english to the students of medicine. this research was performed on the basis of a teacher’s and a number of students’ attitudes and the students’ needs analysis for two reasons: first, to investigate...
15 صفحه اولDiagnosis of Clostridium difficile infection.
TO THE EDITOR—Despite our long-standing interest in earlier tests for Clostridium difficile toxin [1], we believe that polymerase chain reaction (PCR) technology should simply replace other algorithms for the diagnosis of C. difficile infection, as recently outlined in Clinical Infectious Diseases by Kufelnicka and Kirn [2]. We studied 122 consecutive specimens submitted for C. difficile testin...
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ژورنال
عنوان ژورنال: Microbiologia Medica
سال: 2010
ISSN: 2280-6423
DOI: 10.4081/mm.2010.2420